​徳島大学
大学院医歯薬学研究部口腔生命科学分野
フォトニクス健康フロンティア研究院/IPHF　実験腫瘍学部門

Wang C, Sarubo M, Chen S, Kudo Y*.  Partial-EMT in Oral Squamous Cell Carcinoma: Molecular Circuitry and Clinical Translation. Int J Oral Sci 18:15, 2026.

Tsunematsu T, Mouri Y, Shao W, Arakaki R, Jan R, Murano K, Ishimaru N, Guardavaccaro D, Pagano M, Kudo Y*. Sustained chromosomal passenger complex activity preserves pluripotency of human embryonic carcinoma cells. Sci Signal 18: Issue 874, 2025.

Utaijaratrasmi P, Vaeteewoottacharn K, Tsunematsu T, Jamjantra P, Wongkham S, Pairojkul C, Khuntikeo N, Ishimaru N, Thuwajit P, Thuwajit C, Kudo Y*. The microRNA-15a-PAI-2 axis in cholangiocarcinoma-associated fibroblasts promotes migration of cancer cells.​ Mol Cancer 17(1):10, 2018.

Tsunematsu T, Takihara Y, Ishimaru N, Pagano M, Takata T, Kudo Y*. Aurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis. Nat Commun 4:1885, 2013. 

D'Angiolella V, Donate V, Forrester FM, Jeong YT, Pellacani C, Kudo Y, Saraf A, Florens L, Washburn MP, Pagano M. Cyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repair. Cell 149(5):1023-1034, 2012.

Uchida S, Watanabe N, Kudo Y, Yoshioka K, Matsunaga T, Ishizuka Y, Nakagama H, Poon RYC, Yamashita K. SCFßTrcp mediates stress-activated MAPK-induced Cdc25Bdegradation. J Cell Sci 124(16):2816-2825, 2011.

Iizuka S, Kudo Y*, Yoshida M, Tsunematsu T, Yoshiko Y, Uchida T, Ogawa I, Miyauchi M, Takata T. Ameloblastin regulates osteogenic differentiation by inhibiting Src kinase via cross talk between integrin beta 1 and CD63. Mol Cell Biol 31(4):783-792, 2011.

Kudo Y*, Ogawa I, Kitajima S, Kitagawa M, Kawai H, Gaffney PM, Miyauchi M, Takata T. Periostin promotes invasion and anchorage-independent growth in the metastatic process of head and neck cancer. Cancer Res 66(14):6928-6935, 2006.

Kudo Y, Guardavaccaro D, Santamaria PG, Nasu R, Latres E, Bronson R, Richardson A, Yamasaki Y, Pagano M. Role of F-box protein βTrcp1 in mammary gland development and tumorigenesis. Mol Cell Biol 24(18):8184-8194, 2004.

Kudo Y, Kitajima S, Sato S, Miyauchi M, Ogawa I, Takata T. High expression of S-phase kinase-interacting protein 2, human F-box protein, correlates with poor prognosis in oral squamous cell carcinomas. Cancer Res 61(19):7044-7047, 2001.

Kudo Y*, Takata T, Yasui W, Ogawa I, Miyauchi M, Takekoshi T, Tahara E, Nikai H. Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is an indicator of malignant behavior in oral squamous cell carcinoma. Cancer 83(12):2447-2455, 1998. ​

Lauriola A, Steinberg JHE, Sarubo M, Maspero E, Rossi FA, Mouri Y, Pedretti M, Hajisadeghian M, Vettori A, Vitulo N, Assfalg M, D’Onofrio M, Rossi M, Yasue A, Astegno A, Polo S, Santi S, Kudo Y*, Guardavaccaro D*. RNF32 controls the IKK complex and NF-κB signaling in intestinal stem cells. Mol Cell 85: 4254-4267, 2025.

Tsunematsu T, Arakaki R, Kawai H, Ruppert J, Yamada A, Tsuneyama K, Ishimaru N, Earnshaw WC, Pagano M, Kudo Y*. APC/C-Cdh1 is required for the termination of CPC activity upon mitotic exit. J Cell Sci 133(18):jcs251314, 2020

Donato V, Bonora M, Simoneschi D, Sartini D, Kudo Y, Saraf A, Florens L, Washburn MP, Stadtfeld M, Pinton P, Pagano M. The TDH-GCN5L1-Fbxo15-KBP axis limits mitochondrial biogenesis in mouse embryonic stem cells. Nat Cell Biol 19(4):341-351, 2017

Shimizu N, Nakajima NI, Tsunematsu T, Ogawa I, Kawai H, Hirayama R, Fujimori A, Okayasu R, Ishimaru N, Takata T, Kudo Y*. Selective enhancing effect of early mitotic inhibitor 1 (Emi1) depletion on the sensitivity of doxorubicin or X-ray treatment in human cancer cells. J Biol Chem 288(24):17238-17252, 2013.

Kudo Y*, Iizuka S, Yoshida M, Tsunematsu T, Subarnbhesaj A, Siriwardena SB, Tahara H, Ogawa I, Takata T. Matrix metalloproteinase-13 (MMP-13) directly and indirectly promotes tumor angiogenesis. J Biol Chem 287(46):38716-38728, 2012. 

Xu D, Takeshita F, Hino Y, Fukunaga S, Kudo Y, Tamaki A, Takata T, Shimamoto A, Ochiya T, Tahara H. miR-22 represses cancer progression by inducing cellular senescence. J Cell Biol 193(2):409-424, 2011.

Hatano H, Kudo Y*, Ogawa I, Tsunematsu T, Kikuchi A, Abiko Y, Takata T. IFN-induced transmembrane protein 1 promotes the invasion at the early stage of head and neck cancer progression. Clin Cancer Res 14(19):6097-6105, 2008.

Kudo Y*, Kitajima S, Ogawa I, Hiraoka M, Salgolzaei S, Keikhaee MR, Sato S, Miyauchi M, Takata T. Invasion and metastasis of oral cancer cells require methylation of E-cadherin and/or degradation of membranous β-catenin. Clin Cancer Res 10(16):5455-5463, 2004.

Guardavaccaro D, Kudo Y, Boulaire J, Barchi M, Busino L, Donzelli M, Margottin F, Jackson P, Yamasaki L, Pagano M. Control of meiotic and mitotic progression by the F-box protein β-Trcp1 in vivo. Dev Cell 4(6):799-812, 2003. 

Kudo Y*, Takata T, Ogawa I, Sato S, Kaneda T, Takekoshi T, Zhao M, Miyauchi M, Nikai H. p27Kip1 accumulation by inhibition of proteasome function induces apoptosis in oral squamous cell carcinoma cells. Clin Cancer Res 6(3):916-923, 2000.